ALTERNATIVE THIOGLYCOLLATE MEDIUM (USP)

Alternative Thioglycollate Medium is formulated as described in N.I.H. Memorandum, U.S. Pharmacopoeia. This medium is recommended for sterility testing for detecting the presence of viable forms of microorganisms in or on pharmaceutical preparations. This medium is also used for sterility checking for devices having tubes with small lumina. Alternative thioglycollate Medium is generally used for products containing mercurial preservatives when the oxidation reduction indicator is not present or required. Lack of an indicator in the medium avoids possible toxicity to organisms. Alternative Thioglycollate Medium contains sodium thioglycollate that can neutralize the bacteriostatic effect of mercurial preservatives.