Product Code TM 2166
Corynebacterium diphtheriae, also called as Klebs-Loeffler bacillus, is a gram-positive, non-encapsulated, non-sporulated, non-motile facultative anaerobe. It causes infection in humans, leading to diseased condition called diphtheria characterized by an inflammatory lesion and membranous exudates on the mucosa of the upper respiratory tract. C. diphtheriae may show abundant volutin in films from a moist Loeffler serum slope. Preliminary culture on Loeffler Agar is required to induce the characteristic production of abundant granules in C. diphtheriae.
Loeffler Medium was originally devised by Loeffler and was further modified by Perry and Petran and Buck. Loeffler medium enhances primary and secondary isolation and cultivation of fastidious pathogenic microorganisms especially from nose and throat. It also restores virulence and other identifying properties (microscopic and colonial) after they have been lost due to prolonged incubation or repeated sub culturing. It is also used for demonstration of pigmentation and ascospores. The high serum content helps in determining proteolytic activity of organisms.
for the cultivation of Corynebacterium diffhtheriae
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