LOEFFLER SERUM MEDIUM BASE

Product Code TM 2166

  • Description

    Corynebacterium diphtheriae, also called as Klebs-Loeffler bacillus, is a gram-positive, non-encapsulated, non-sporulated, non-motile facultative anaerobe. It causes infection in humans, leading to diseased condition called diphtheria characterized by an inflammatory lesion and membranous exudates on the mucosa of the upper respiratory tract. C. diphtheriae may show abundant volutin in films from a moist Loeffler serum slope. Preliminary culture on Loeffler Agar is required to induce the characteristic production of abundant granules in C. diphtheriae.
    Loeffler Medium was originally devised by Loeffler and was further modified by Perry and Petran and Buck. Loeffler medium enhances primary and secondary isolation and cultivation of fastidious pathogenic microorganisms especially from nose and throat. It also restores virulence and other identifying properties (microscopic and colonial) after they have been lost due to prolonged incubation or repeated sub culturing. It is also used for demonstration of pigmentation and ascospores. The high serum content helps in determining proteolytic activity of organisms.

  • Principle

    for the cultivation of Corynebacterium diffhtheriae

  • Microorganism

    • Corynebacterium diphtheriae
    • Corynebacterium diphtheriae type gravis
    • Corynebacterium diphtheriae type mitis
    • Pseudomonas aeruginosa
    • Staphylococcus aureus subsp. aureus
  • Industry

    • NA
  • Regulation

    • NA
  • Pack Size

    • 100 gm
    • 500 gm
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